潘昕

潘昕

教授

研究領域:微針經皮藥物遞送系統;肺部藥物遞送系統

辦公電話: 020-39943427

聯系郵箱: panxin2@mail.sysu.edu.cn

聯系方式

辦公電話:020-39943427

電子郵箱:panxin2@mail.sysu.edu.cn    

辦公地址:廣州市大學城外環東路132号太阳集团1088vip214A室

簡單介紹

潘昕,太阳集团1088vip教授,博導,教育部長江學者獎勵計劃青年學者、廣東省傑出青年、珠江科技新星人才。2011年畢業于中山大學,獲藥劑學博士學位,後留校任教,美國The University of Texas at Austin訪問學者。主要研究方向為藥物新劑型和新技術。以單獨通訊/共同通訊作者身份,在J Control Release, ACS Nano, Acta Pharm Sin B等發表論文發表SCI論文60餘篇,獲得授權專利27項,其中12項專利已實現有償轉化。作為主要完成人,榮獲2019中國産學研合作創新成果一等獎(2/10)、2020中國發明創業創新獎二等獎(2/6)、2018廣東省科學技術獎二等獎(3/10)、2016 年中國産學研合作創新成果二等獎(3/7)等獎項,個人獲中國藥物制劑大會青年藥劑學獎。10餘次應邀在國際國内作學術報告,包括第十六屆中國藥物制劑大會(中國長沙,2022)、Particulate Processes in the Pharmaceutical Industry IV(Potsdam, Germany, 2016)等。主持科研項目十餘項,包括國家自然科學基金面上項目(3項)、廣東省自然科學基金傑出青年項目、“十三五”國家重大新藥創制專項子課題、國家863計劃子課題、廣東省重點領域研發計劃子課題及廣東省團隊項目等。指導的學生曾獲全國專業碩士優秀論文獎、中山大學優秀博士論文獎、中國博士後創新人才計劃等。學術兼職包括中國藥學會藥物制劑專業委員會青年委員、廣東省藥學會藥物制劑委員會秘書長、《Pharmaceutics》編委、《Asian Journal of Pharmaceutical Science》青年編委、《Chinese Chemical Letters》青年編委、《藥學進展》青年編委等。

研究方向

微針經皮藥物遞送系統;肺部藥物遞送系統

教育經曆

2006.09-2011.06     博士,藥劑學, 中山大學,廣州 

2002.09-2006.07     學士,藥學,中山大學,廣州

工作經曆

2024.4至今                  太阳集团1088vip    教授

2017-2018                  美國德克薩斯奧斯汀分校太阳集团1088vip  訪問學者

2015-2024.4              太阳集团1088vip    副教授

2013.07-2015.12        太阳集团1088vip   講師

2011.07-2013.06        太阳集团1088vip    師資博士後

社會/學術任職

1. 《Pharmaceutics》編委

2. 《Asian Journal of Pharmaceutical Science》青年編委

3. 《Chinese Chemical Letters》青年編委

4. 《藥學進展》青年編委

5. 中國藥學會藥物制劑專業委員會 青年委員

6. 廣東省藥學會藥物制劑委員會 秘書長

7. 廣州市市場監督管理局食品藥品特種設備安全專家委員會 委員

8. 廣州市納米生物醫藥科技促進會 理事

9. 第二屆工業藥學與臨床藥學研讨會組委會 組長

10. 美國藥學科學家協會中山大學學生分會 (AAPS Sun Yat-Sen University Student Branch )  發起人

榮譽獎勵

1. 中國産學研合作創新成果一等獎(第二完成人)

2. 中國發明創業創新獎二等獎(第二完成人)

3. 廣東省科學技術獎二等獎(第三完成人)

4. 中國藥物制劑大會青年藥劑學獎

5. 《Acta Pharm Sin B》傑出論文獎

6. 廣州市“珠江科技新星”

 

科研項目

  1. 活性氧氣微泡驅動微針遞藥系統用于瘢痕疙瘩的高效治療機制研究,國家自然科學面上項目,49萬元,項目負責人,項目編号:82373803,2024/01-2027/12。
  2. 可控晶格的動态智能液晶系統用于軟組織缺損修複及其機制研究,國家自然科學面上項目,55萬元,項目負責人,項目編号:81973263,2020/01-2023/12。
  3. 抗腫瘤新型納米微針藥物制劑關鍵技術及産業化研究,廣東省重點領域研發計劃,210/700萬元,子課題負責人,項目編号:2019B020204002,2019/10-2022/12。
  4. “長效緩控釋微球産業化共性關鍵技術與創新制劑研發-注射用促紅細胞生成素微球,國家重大新藥創制專項子課題,264.90萬元,項目負責人,項目編号:2017ZX09201004-017,2017/01-2020/12。
  5. “幹粉吸入劑二元載體表面微結構的定向構建及其增效機理的研究”,國家自然基金面上項目,51萬,項目負責人,2017/01-2020/12。
  6. “藥食同源多組分功能因子在臨床營養制劑中的穩定性研究、工藝研究及中試、産品質量評價”,國家高技術研究發展計劃(863 計劃)子課題,90萬元,項目負責人,項目編号:2014AA022204, 2014/01-2016/12。
  7. “基于超細微粒制備技術的微粒成丸機理研究及其在微丸片中的應用”,國家自然科學基金青年基金,23萬元,項目負責人,項目編号:81202476,2013/01-2015/12。
  8. “超細微粒制造系統制備骨架微丸的機理研究及其在口崩微丸片産業化中的應用”,廣州市珠江科技新星,30萬元,項目負責人,項目編号:1317000297,2014/04-2017/03。
  9. “智能型低溫超微粒藥物制備系統的設計及理論研究”,廣東省自然科學基金團隊項目,50/300萬元,核心成員等同于子課題負責人,項目編号:2016A030312013,2016/01-2018/12。
  10. “基于超細微粒制備技術的微粒成球機理研究及其在石杉堿甲口崩型緩釋微丸片中的應用”,教育部博士點基金新教師類,4萬元,項目負責人,項目編号:20120171120046,2012/01-2014/12。
  11. “基于超細微粒制備技術的微粒成丸機理及其在口崩型緩釋微丸片的中的應用”,中國博士後科學基金委,5萬元,項目負責人,項目編号:2012M511625,2011/01-2013/12。
  12. “石杉堿甲口崩型緩釋微丸片的研究”,廣東省衛生廳醫學科研基金,0.5萬元,項目負責人,項目編号:B2012079,2012/07-2014/06。
  13. “多孔/微粗糙甘露醇載體的形成機制及其在幹粉吸入劑中的應用”,高校基本科研業務費中山大學青年教師培育項目,15萬元,項目負責人,項目編号:16ykpy23,2016/01-2018/12。

論著專利

部分代表性論文(近三年):

  1. D Yang#, M Chen#, Y Sun, C Shi, W Wang, W Zhao, T Wen, T Liu, J Fu, C Lu, C Wu, G Quan*, X Pan*. Microneedle-assisted vaccination combined with autophagy regulation for antitumor immunotherapy. J Control Release, 2023, 357: 641-654.
  2. W Wang#, F Fu#, Z Huang, W Wang, M Chen, X Yue, J Fu, X Feng, Y Huang, C Wu, X Pan*. Inhalable biomimetic protein corona-Mediated nanoreactor for self-amplified lung adenocarcinoma ferroptosis therapy,ACS Nano, 2022, 16:8370.
  3. W Wang#, Z Huang#, Y Huang, X Zhang, J Huang, Y Cui, X Yue, C Ma, F Fu, W Wang, C Wu, X Pan*. Pulmonary delivery nanomedicines towards circumventing physiological barriers Strategies and characterization approaches,Advanced Drug Delivery Reviews, 2022, 185, 114309:1-28.
  4. X Zhang, Y Cui, R Liang, G Wang, X Yue, Z Zhao, Z Huang,Y Huang, J. Geng, X Pan*, C Wu. Novel approach for real-time monitoring of carrier based DPIs delivery process via pulmonary route based on modular modified Sympatec HELOS,Acta Pharmaceutica Sinica B, 2020, 10,7:1331-1346.
  5. X Feng#, D Xian#, J Fu, R Luo, W Wang, Y Zheng, Q He, Z Ouyang, S Fang, W Zhang, D Liu, S Tang, G Quan, J Cai, C Wu, C Lu*, X Pan*. Four-armed host-defense peptidomimetics-augmented vanadium carbide MXene-based microneedle array for efficient photo-excited bacteria-killing. Chemical Engineering Journal, 2023, 456(15): 141121.
  6. T Peng, Y Chen, W Hu, Y Huang, M Zhang, C Lu*, X Pan*, C Wu*. Microneedles for Enhanced Topical Treatment of Skin Disorders: Applications, Challenges, and Prospects. Engineering. 2023, In press.
  7. J Fu, Y Zhou, T Liu, W Wang, Y Zhao, Y Sun, Y Zhang, W Qin, Z Chen, C Lu, G Quan, C Wu, X Pan*. A triple-enhanced chemodynamic approach based on glucosepowered hybrid nanoreactors for effective bacteria killing. Nano Research, 2023, In press.
  8. X Gao#, F Zhang#, Y Huang, W Hu, Y Chen, L Jiang, X Pan, C Wu*, C Lu*, T Peng*. Site-specifically launched microneedles for the combined treatment of psoriasis-diabetic comorbidity. ACS Appl Mater Inter, 2023, 15(40):46613-46625
  9. Y Huang, T Peng*, Y Chen, F Zhang, W Hu, X Gao, H Chen, P Tang, C Wu, X Pan*. An oxygen reservoir-irrigated photoimmunotherapy of malignant melanoma. Nano Res, 2023, 16:2875-2884
  10. Y Huang#, Z Chang#, X Xia#, Z Zhao, X Zhang*, Z Huang*, C. Wu, X. Pan*. Current and evolving knowledge domains of cubosome studies in the new millennium. J Nanopart Res. 2023; 25: 176
  11. M Guo, T Peng*, C Wu, X Pan, Z Huang*. Engineering ferroptosis inhibitors as inhalable nanomedicines for the highly efficient treatment of idiopathic pulmonary fibrosis. Bioengineering. 2023; 10(6): 727.
  12. Z Chang#, W Wang#, Z Huang*, Y Huang, C Wu, X Pan*. Lecithin reverse micelle is promising in constructing carrier particles for protein drugs encapsulated pressurized metered-dose inhalers. Adv Therapeut. 2023; Accepted Manuscript.
  13. W Wang#, J Zeng#, P Luo#, J Fang, Q Pei, J Yan, C Zhu, W Chen, Y Liu, Z Huang*, Y Huang*, C Wu, X Pan*. Engineered lipid liquid crystalline nanoparticles as an inhaled nanoplatform for mucus penetration enhancement. Drug Deliv Transl Re. 2023; Accepted Manuscript.
  14. W Wang#, W Wang#, S Jin, F Fu, Z Huang*, Y Huang*, C Wu, X Pan*. Open pocket and tighten holes: Inhalable lung cancer-targeted nanocomposite for enhanced ferroptosis-apoptosis synergetic therapy. Chem Eng J. 2023; 458: 141487.
  15. Y Sun#, M Chen#, D Yang, W Qin, G Quan*, C Wu, X Pan*. Self-assembly nanomicelle-microneedle patches with enhanced tumor penetration for superior chemo-photothermal therapy. Nano Research, 2022, 15: 2335-2346.
  16. B Niu#, Y Zhou#, K Liao, T Wen, S Lao, G Quan*, X Pan*, C Wu*. “Pincer movement”: reversing cisplatin resistance based on simultaneous glutathione depletion and glutathione s-transferases inhibition by redox-responsive degradable organosilica hybrid nanoparticles. Acta Pharm Sin B, 2022, 12(4): 2074-2088.
  17. J Fu, T Liu, X Feng, Y Zhou, M Chen, W Wang, Y Zhao, C Lu, G Quan, J Cai, X Pan*, C Wu. A perfect pair: stabilized black phosphorous nanosheets engineering with antimicrobial peptides for robust multidrug resistant bacteria eradication. Adv Healthcare Mater, 2022, 2101846.
  18. B Niu, K Liao, Y Zhou, T Wen, G Quan*, C Wu, X Pan*. Cellular defense system-destroying nanoparticles as a platform for enhanced chemotherapy against drug-resistant cancer. Materials Science and Engineering: C, 2021, 131, 112494.
  19. Y Zhou#, B Niu#, Y Zhao, J Fu, T Wen, K Liao, G Quan, X Pan*, C Wu*. Multifunctional nanoreactors-integrated microneedles for cascade reaction-enhanced cancer therapy. J Controll Release, 2021, 339: 335-349.
  20. B Niu, K Liao, Y Zhou, T Wen, G Quan, X Pan*, C Wu*. Application of glutathione depletion in cancer therapy: Enhanced ROS-based therapy, ferroptosis, and chemotherapy. Biomaterials, 2021, 277: 121110.
  21. T Wen, Z Lin, Y Zhao, Y Zhou, B Niu, C Shi, C Lu, Xi Wen, M Zhang, G Quan,* C Wu, X Pan*. Bioresponsive nanoarchitectonics-integrated microneedles for amplified chemo-photodynamic therapy against acne vulgaris. ACS Appl. Mater. Interfaces, 2021, 13, 41, 48433-48448.
  22. Y Zhao#, Y Zhou#, D Yang, X Gao, T Wen, J Fu, X Wen, G Quan*, X Pan*, C Wu. Intelligent and spatiotemporal drug release based on multifunctional nanoparticle-integrated dissolving microneedle system for synergetic chemo-photothermal therapy to eradicate melanoma. Acta Biomaterialia, 2021, 2021, 135: 164-178.
  23. S Luo, Y Zhao, K Pan, Y Zhou, X Wen, G Quan*, X Wen, X Pan*, C Wu. Microneedle-mediated delivery of MIL-100(Fe) as a tumor microenvironment-responsive biodegradable nanoplatform for O2 evolving chemophototherapy. Biomater Sci, 2021, 9, 6772-6786.
  24. P Yang, M Chen, W Qin, C Shi, X Bai, G Quan*, X Pan*, C Wu. Effective photothermal therapy mediated by indocyanine green nanoparticle tip-loaded microneedles to enhance checkpoint inhibitors immunotherapy of melanoma. ACS Applied Nano Materials, 2021, 4(6): 5921-5931.
  25. M Chen#, D Yang#, Y Sun#, T Liu, W Wang, J Fu, Q Wang, X Bai, G Quan*, X Pan*, C Wu*. In situ self-assembly nanomicelle microneedles for enhanced photoimmunotherapy via autophagy regulation strategy. ACS Nano, 2021, 15, 2, 3387-3401.
  26. B Yang, Y Dong, Y Shen, A Hou, G Quan*, X Pan*, Bilayer dissolving microneedle array containing 5-fluorouracil and triamcinolone with biphasic release profile for hypertrophic scar therapy, Bioactive Materials, 2021, 6,8:2400-2411.
  27. T Wen#, G Quan#, B Niu, Y Zhou, Y Zhao, C Lu, X Pan*, C Wu*. Versatile nanoscale metal-organic frameworks (nMOFs): an emerging 3D nanoplatform for drug delivery and therapeutic applications. Small, 2021, 17(8): 2005064
  28. Y Shi, X Feng, L Lin, J Wang, J Chi, B Wu, G Zhou, F Yu, Q Xu, D Liu, G Quan, C Lu*, X Pan*, J Cai*, C Wu*. Virus-inspired surface-nanoengineered antimicrobial liposome: A potential system to simultaneously achieve high activity and selectivity. Bioactive Materials, 2021, 6(10): 3207-3217.
  29. T Peng, Y Huang, X Feng, C Zhu, Y Shi, X Wang, X Bai, X Pan*, C Wu*. TPGS/hyaluronic acid dual functionalized PLGA nanoparticles delivered through dissolving microneedles for markedly improved chemophotothermal combined therapy of superficial tumor. Acta Pharm Sin B, 2021, 11(10):3297-3309、
  30. S Wei, G Quan*, C Lu, X Pan*, C Wu. Dissolving microneedles integrated with pH-responsive micelles containing aiegen with ultra-photostability for enhancing melanoma photothermal therapy. Biomater Sci, 2020, 8(20): 5739-5750.
  31. B Wu, J Fu, Y Zhou, S Luo, Y Zhao, G Quan*, X Pan*, C Wu. Tailored core-shell dual metal-organic frameworks as a versatile nanomotor for effective synergistic antitumor therapy. Acta Pharm Sin B, 2020, 10(11): 2198-2211.
  32. W Qin#, G Quan#, Y Sun, M Chen, P Yang, D Feng, T Wen, X Hu, X Pan*, C Wu. Dissolving microneedles with spatiotemporally controlled pulsatile release nanosystem for synergistic chemo-photothermal therapy of melanoma. Theranostics, 2020, 10(18): 8179-8196.
  33. M Chen#, G Quan#, Y Sun, D Yang, X Pan*, C Wu*. Nanoparticles-encapsulated polymeric microneedles for transdermal drug delivery. J Control Release, 2020, 325: 163-175.
  34. M Chen#, G Quan#, T Wen, P Yang, W Qin, H Mai, Y Sun, C Lu, X Pan*, C Wu*. Cold to hot: binary cooperative microneedle array-amplified photoimmunotherapy for eliciting antitumor immunity and the abscopal effect. ACS Appl Mater Inter, 2020, 12(29): 32259-32269
  35. Z Huang, Y Huang, W Wang, F Fu, W Wang, S Dang, C Li, C Ma, X Zhang, Z Zhao, X Pan*, C Wu. Relationship between particle size and lung retention time of intact solid lipid nanoparticle suspensions after pulmonary delivery. J Control Release. 2020; 325: 206-222.
  36. W Wang#, Z Huang#, K Xue, J Li, W Wang, J Ma, C Ma, X Bai, Y Huang*, X Pan**, C Wu. Development of aggregation-caused quenching probe-loaded pressurized metered-dose inhalers with fluorescence tracking potentials. AAPS Pharmscitech. 2020; 21:296.
  37. Z Huang#, C Ma#, M Wu#, X Li, C Lu, X Zhang, X Ma, Y Yang, Y Huang*, X Pan**, C Wu. Exploring the drug-lipid interaction of weak-hydrophobic drug loaded solid lipid nanoparticles by isothermal titration calorimetry. J Nanopart Res. 2020; 22(3): 1-14.
  38. T Peng#, Y Huang#, X Feng, C Zhu, X Ma, X Wang, X Bai, X Pan*, C Wu*. Dissolving microneedles loading TPGS biphasic functionalized PLGA nanoparticles for efficient chemo-photothermal combined therapy of melanoma. Adv Therap 2020, 3:1900190
  39. J Wang#, C Lu #, Y Shi, X Feng, B Wu, G Zhou, G Quan, X Pan,* J Cai,* and C Wu.* Structural Superiority of Guanidinium-Rich Four-Armed Copolypeptides: Role of Multiple Peptide-Membrane Interactions in Enhancing Bacterial Membrane Perturbation and Permeability. ACS Applied Materials & Interfaces. 2020, 12, 18363-18374.
  40. M Sun#, C Zhu#, J Long, C Lu*, X Pan* and C Wu. PLGA microsphere-based composite hydrogel for dual delivery of ciprofloxacin and ginsenoside Rh2 to treat Staphylococcus aureus-induced skin infections. Drug Delivery, 2020, 27(1): 632-641.
  41.  B Wu, J Fu, Y Zhou, Y Shi, J Wang, X Feng, Y Zhao, G Zhou, C Lu*, G Quan*, X Pan, C Wu. Metal–organic framework-based chemo-photothermal combinational system for precise, rapid and efficient antibacterial therapeutics. Pharmaceutics 2019, 11, 463.
  42. Y Zhou#, Q Fang#, B Niu, B Wu, Y Zhao, G Quan*, X Pan*, C Wu. Comparative studies on amphotericin B nanosuspensions prepared by a high pressure homogenization method and an antisolvent precipitation method. Colloid Surface B. 2018, 172:372-379.
  43. B Niu, Y Zhou, T Wen, G Quan*, V Singh, X Pan*, C Wu. Proper functional modification and optimized adsorption conditions improved the DNA loading capacity of mesoporous silica nanoparticles, Colloid Surface A. 2018, 548:98-107.
  44. Y Zhou#, G Quan#, QWu, X Zhang, B Niu, B Wu, Y Huang, X Pan*, C Wu*. Mesoporous silica nanoparticles for drug and gene delivery. Acta Pharm Sin B. 2018, 8(2):165-177.
  45. Z Huang, H Wu, C Zhu, Y Huang, X Pan, C Wu*. Salmon calcitonin containing pressurized metered-dose inhaler based on anhydrous reverse micelle nanoparticles. Nanomed-Nanotechnol. 2018; 14: 1831.
  46. Z Huang, Y Huang*, C Ma, X Ma, X Zhang, L Lin, Z Zhao, X Pan**, C Wu. Endotracheal aerosolization device for laboratory investigation of pulmonary delivery of nanoparticle suspensions: In vitro and in vivo validation. Mol Pharmaceut. 2018; 15: 5521-5533.
  47. Z Huang#, H. Wu#, B Yang, L Chen, Y Huang, G Quan, C Zhu, X Li, X Pan*, C Wu. Anhydrous reverse micelle nanoparticles: New strategy to overcome sedimentation instability of peptide-containing pressurized metered-dose inhalers. Drug Deliv. 2017; 24(1): 527-538.
  48. Y Dong, P Dong, D Huang, L Mei, Y Xia, Z Wang, X Pan*, G Li, C Wu*, Fabrication and characterization of silk fibroin-coated liposomes for ocular drug delivery, Eur J Pharm Biopharm, 2015,91:82-90.
  49. G Quan, Xi Pan, Z Wang, Q Wu, G Li, L Dian, B Chen*, C Wu*, Lactosaminated mesoporous silica nanoparticles for asialoglycoprotein receptor targeted anticancer drug delivery, J Nanobiotech, 2015,13:7-18.
  50. Y Huang, C Zhu, G Li, X Pan*, C Wu. Metoprolol tartrate sustained-release binary matrix microspheres for oral administration produced by novel ultra-fine particle processing system, Powder Technol, 2015, 285: 44-50.
  51. C Zhu, Y Huang, X Zhang, L Mei, G Li, X Pan*, C Wu *, Comparative studies on exenatide-loaded poly (D, L-lactic-co-glycolic acid) microparticles prepared by a novel ultra-fine particle processing system and spray drying. Colloid Surface B Biointerface, 2015, 132:103-110.
  52. J Ji, J Zhang, J Chen, Y Wang, X Wang, N Dong, C Hu, H Chen, G Li, X Pan*, Wu C. Preparation and stabilization mechanism of emulsions stabilized by mixed sodium caseinate and soy protein isolate, Food Hydrocolloid, 2015, 51: 156-165.
  53. X Pan, K Han, X Peng, Z Yang, L Qin, C Zhu, C Wu*, Nanostructed cubosomes as advanced drug delivery system, Curr Pharm Design, 2013, (8): 6290-6297
  54. D Huang, L Wang, Y Dong, X Pan*, G Li, C Wu*, A novel technology using transscleral ultrasound to deliver protein loaded nanoparticles, Eur. J. Pharm. Biopharm. 2014,88:104-115.
  55. L Dian, Z Yang, F Li, Z Wang, X Pan*, X Peng, X Huang, Z Guo, G Quan, X Shi, B Chen, G Li, C Wu*, Cubic phase nanoparticles for sustained release of ibuprofen: formulation, characterization, and enhanced bioavailability study, Int. J. Nanomed. 2013,8: 845–854.
  56. W Wang#, Z Zhong#, Z Huang*, F Fu, W Wang, L Wu, Y Huang*, C Wu, X Pan*. Two different protein corona formation modes on Soluplus® nanomicelles. Colloid Surface B. 2022; 218:112744.
  57. W Wang#, Z Huang#, Y Huang#, X Zhang, J Huang, Y Cui, X Yue, C Ma, F Fu, W Wang, C Wu, X Pan*. Pulmonary delivery nanomedicines towards circumventing physiological barriers: Strategies and characterization approaches. Adv Drug Deliver Rev. 2022; 185: 114309.
  58. W Wang#, H Liu#, Z Huang*, F Fu, W Wang, L Wu, Y Huang*, C Wu, X Pan*. The effect of organic ligand modification on protein corona formation of nanoscale metal organic frameworks. Chinese Chem Lett. 2022; 33: 4185-4190.
  59. Z Huang#, F Fu#, L Wu#, W Wang, W Wang, C Shi, Y Huang*, X Pan*, C Wu. Bibliometric landscape of the researches on protein corona of nanoparticles. Front Mater Sci. 2021; 15: 477-493.
  60. W Wang, B Yang, Z Huang*, Y Huang, P Hu, X Pan*, C Wu. Investigating the effect of particle size on cellular uptake by aggregation-caused quenching probes encapsulated solid lipid nanoparticles, inhaled. J Pharm Innov. 2021.

授權專利:

  1. 吳傳斌,吳涵,潘昕。水溶性藥物無水反膠束納米粒及其混懸型氣霧劑的制備方法。ZL201310154231.3,授權公告日:20150506
  2. 吳傳斌,吉娟,潘昕。雙蛋白共乳化體系及其制備方法和應用,ZL 201410513452.X,授權公告日:20160622
  3. 潘昕,吳傳斌,周煥彬,陳嘉樹。益生菌微膠囊及其制備方法和應用,ZL 201510708165.9,授權公告日:20180406
  4. 潘昕,黃瑩,彭婷婷,張雪娟,表面納米級粗糙結構的顆粒及其制備方法和應用。ZL 201610013832.6,授權公告日:2018.11.09
  5. 潘昕,黃瑩,梅麗玲,緩釋立方液晶液體硬膠囊及其制備方法。ZL 201610013835.X,授權公告日:2018.12.11
  6. 潘昕,鄭騰羿,吳傳斌。用于根管消毒的溶緻液晶前體及其制備方法和應用,ZL 201610237606.6,授權公告日:2018.12.11
  7. 潘昕,陳龍楷,馮地桑,黃瑩,吳涵,吳傳斌。磷脂蛋白質微粒複合微球及其制備方法,ZL 201610031750.4,授權公告日:2018.12.11
  8. 吳傳斌,謝業城,潘昕,黃瑩,梅麗玲,陳航平,王倍,李娜。局部麻醉藥的立方液晶原位凝膠注射劑及其制備方法,ZL 201611131813.X,授權公告日:2020.01.21
  9. 吳傳斌,牛博藝,吳巧利,權桂蘭,潘昕。非諾貝特固體分散體及其制備方法和應用,ZL 201611200910.X,授權公告日:2020.01.14
  10. 吳傳斌,馮地桑,潘昕,權桂蘭,黃瑩,陳航平。固體分散體及其制備方法和應用,ZL 201611185254.0,授權公告日:2019.10.18
  11. 吳傳斌,張雪娟,趙紫玉,潘昕,黃瑩,彭婷婷。多孔結構的載體顆粒及其制備方法和應用,ZL 201611124085.X,授權公告日:2019.09.20
  12. 潘昕,彭婷婷,楊佩佩,朱春娥,吳傳斌。石杉堿甲骨架微粒、口崩片及其制備方法,ZL201610944569.2,授權公告日:2019.04.19
  13. 潘昕,梅麗玲,楊蓓蓓,吳傳斌,黃瑩,謝業城。液晶納米粒前體微粒、自組裝液晶納米粒及其制備方法,ZL 201610887832.9,授權公告日:2019.06.18
  14. 吳傳斌,楊莉,李彥蓉,潘昕,黃瑩,陳航平。馬來酸噻嗎洛爾立方液晶納米粒滴眼液及其制備方法,ZL 201611227982.3,授權公告日:2019.09.20
  15. 吳傳斌,侯嫒琳,潘昕,權桂蘭,黃瑩,李露,陳航平。醋酸奧曲肽幹粉吸入制劑及其制備方法,ZL 201611141634.4,授權公告日:2020.10.13
  16. 吳傳斌,趙紫玉,張雪娟,黃瑩,潘昕。防潮抗濕的低密度載體顆粒及其制備方法和應用,中國專利号201611185899.4,授權公告日:2020.10.13
  17. 吳傳斌,湛正文,權桂蘭,潘昕,陳航平。中空介孔二氧化矽納米粒、納米載體及其制備方法,中國專利号201611141631.0,授權公告日:2020.06.16
  18. 吳傳斌,王倍,張曉旭,潘昕,權桂蘭,陳航平。三元基因傳遞系統的凍幹制劑及其制備方法,中國專利号201611207547.4,授權公告日:2020.10.23
  19. 李革,周煥彬,李順怡,潘昕,朱春娥,陳航平。 耐酸、穩定的益生菌微膠囊及其制備方法和應用。中國:201611254327.7,授權公告日:2020.11.17
  20. 吳傳斌,梅麗玲,潘昕,黃瑩,陳錦填,史旋,景卉。冬淩草甲素立方液晶納米粒及其制備方法,中國專利号201611122471.5,授權公告日:2020.10.13
  21. 吳傳斌,林師麒,權桂蘭,潘昕,蔡炳貞,侯嫒琳,楊佩佩。胸腺五肽可溶性微針及其制備方法,ZL 201710393418.7,授權公告日:2020.01.07
  22. 吳傳斌,李靜,朱春娥,潘昕,楊莉,董妮。蛋白多肽類藥物長效微球及其制備方法,ZL 201810522338.1,授權公告日:2020.09.29
  23. 吳傳斌,楊莉,朱春娥,龍婕妤,李靜,潘昕,孫銘昊。共載鹽酸阿黴素納米粒和人參皂苷rh2的複合微球及其制備方法,ZL 201810474916.9,授權公告日:2020.09.08

學術交流

大會報告:

1) Study on Delivering Macromolecule Drugs,The 1st Diwus Forum on Pharmaceutical Technology, Guangzhou, China, 10 April, 2017.

2) Influence of Polymers on the Dual Recrystallizations and Physicochemical Stability of Spray-dried Amorphous Solid Dispersion. 2016年中國藥學大會, 中國北京。

3) 溶緻液晶凝膠系統的研究及應用,2016中國藥學大會,大會報告,2016年12月,中國北京。

4) The Design and Stabilized Peptide Drugs Used in Pressurized Metered Dose Inhalers(pMDI),2016中國藥學大會,大會報告,2016年11月,中國南京。

5) 幹粉吸入劑納米粗糙載體的構建及其提高藥物傳遞效率的機理研究,中國顆粒學會學術年會暨海峽兩岸顆粒技術研讨會,大會報告,2016年8月,中國成都。

6) Dry Powder Inhaler Carrier with Nano-metered Topography Roughness Surface and its Enhancement of Lung Delivery Efficiency, Asian Graduate Congress   on Pharmaceutical Technology, July 9-13, 2016, Singapore.

7) Peptide drug formulation design based on pMDIs, 2015 SYSU-RMIT Joint Symposium, Nov 17-18,2015, Guangzhou China.

8) 蛋白質多肽氣霧給藥系統的設計與評價,第二屆全國生物顆粒研讨會,大會報告,2015年12月,中國廣州。

9) Spray-dried Mannitol-Chitosan as Blend Carrier for Dry Powder Inhalers, Particulate Processes in the Pharmaceutical Industry IV, Sep 11-14, 2014, Potsdam, Germany.

10) Ultra-fine Particle Process System and Its Application for the Drug-containing Microspheres, The 7th World Congress of Particle Technology, May 11-14, 2014, Beijing, China.

11) 臨床營養十三五863重大項目立項前期論證會議,大會報告,2013年3月,中國北京。

12) 微丸片制劑産業化技術,中國顆粒學會第八屆學術年會,分會場報告,2012年9月,中國杭州。