黃佳國，教授，博士生導師，入選國家重大人才計劃青年項目，中山大學‘百人計劃’中青年傑出人才項目、‘歐盟瑪麗居裡學者’及廣東省珠江人才計劃引進創新團隊核心成員。博士畢業于德國海德堡大學，随後在德國海德堡大學及新加坡南洋理工大學從事博士後研究。2021年9月加入太阳集团1088vip。主持國家自然科學基金和廣東省自然科學基金等多項科研項目。入選全球前2%頂尖科學家榜單。迄今共發表SCI論文70餘篇，申請發明專利10項。其中于第一及通訊作者身份發表論文30多篇，包括Nature Materials (2019, 2022)，Nature Reviews Chemistry (2021)，Angew. Chem. Int. Ed.，Adv. Mater., ACS nano, Adv. Func. Mater., Chemical science等，成果多次被Nat. Rev. Nephrol、Nat. Mater. 等期刊媒體作為亮點進行評述。

課題組網址/Group website：https://www.x-mol.com/groups/huanglab-online

ORCID: https://orcid.org/0000-0003-4012-4406

Google Scholar Profile: https://scholar.google.de/citations?user=ElAPm6sAAAAJ&hl=zh-CN

招生招聘信息

1. 課題組2024年招收碩士和博士若幹，歡迎咨詢報考。

2. 課題組長期招聘具有藥學，化學，分子影像學，分子生物學，生物材料學，基礎醫學背景，對疾病診療領域感興趣的博士後和專職研究員，待遇從優。

研究方向

生物醫學技術（包括分子探針、診斷試劑及體外檢測設備/技術）的開發及其在重大疾病中的診斷，監測和治療應用。

科研項目

國家重大人才計劃-青年項目

國家重點研發計劃-青年科學家項目

國家自然科學基金-青年項目

國家自然科學基金-面上項目

廣東省‘珠江人才計劃’創新創業團隊

廣東自然科學基金面上項目

廣州市重點領域研發計劃-健康醫療重大科技專項

中山大學百人計劃‘中青年傑出人才項目’

中央高校基本科研業務費-青年拔尖科研人才培育項目

教育背景及工作經曆

2017. 06–2021.05  新加坡南洋理工大學   博士後研究員

2016. 06–2017.05  德國海德堡大學       博士後研究員

2012. 10– 2016. 05  德國海德堡大學      博士

2009. 09 - 2012. 07  中南大學           理學碩士

2005. 09 - 2009. 07  南昌大學           理學學士

科研成果：代表性論著                                        

  1. Weiping Xu#, Shujuan Yi#, Jie Liu, Yuyan Jiang, Jiaguo Huang*. Nitrile-aminothiol bioorthogonal near-infrared fluorogenic probes for ultrasensitive in vivo imaging. Nature Communications. 2024, DOI : 10.1038/s41467-024-55452-y.
  2. Mengya Yu#, Lijuan Zhu#, Guoqi Dong, Jianjiao Chen, Bankang Ruan, Yi Liu, Shujuan Yi, Zhenqi Meng, Guanjian Chen, Weiping Xu*, Jiaguo Huang*, Fanghai Han*. Spatiotemporal Mapping of Lymphatic Metastases in Gastric Cancer Using Tumor-trackable and Enzyme-activatable Near-infrared Fluorescent Nanoprobes. ACS nano. 2024, DOI : 10.1021/acsnano.4c12915.
  3. Ya Zhou#, Weiping Xu#, Bankang Ruan, Lijuan Zhu, Yuyan Jiang, Hui Cai, Jiaguo Huang*. Molecular Imaging of Renin Activity using Fluorogenic Nanoprobes for Precise Antihypertensive Therapy. Angew. Chem. Int. Ed. 2024, DOI: 10.1002/anie.202416002. (IF= 16.82)
  4. Yi Liu#, Shanchao Diao#, Bankang Ruan#, Ya Zhou#, Mengya Yu, Guoqi Dong, Weiping Xu, Lulu Ning, Wen Zhou, Yuyan Jiang, Chen Xie*, Quli Fan*, Jiaguo Huang*. Molecular Engineering of Activatable NIR-II Hemicyanine Reporters for Early Diagnosis and Prognostic Assessment of Inflammatory Bowel Disease. ACS nano 2024, 18(11), 8437-8451. (IF= 17.1)
  5. Ya Zhou#, Lijuan Zhu#, Biaoxiang Liu, Weiping Xu, Xingyue Yang, Yi Liu, Bankang Ruan, Shujuan Yi, Baoshuai Liang, Guoqi Dong, Jiaguo Huang*. Tailored Zwitterionic Hemicyanine Reporters for Early Diagnosis and Prognostic Assessment of Acute Renal Failure. Angew. Chem. Int. Ed. 2023, 62, e202315457. (IF= 16.82)
  6. Bankang Ruan, Mengya Yu, Ya Zhou, Weiping Xu, Yi Liu, Biaoxiang Liu, Lijuan Zhu, Shujuan Yi, Yuyan Jiang, Jiaguo Huang*. Size-transformable superoxide-triggered nanoreporters for crosstalk-free dual fluorescence/chemiluminescence imaging and urinalysis in living mice. Angew Chem Int Edit. 2023, e202305812. (IF=16.82)
  7. Jiaguo Huang, Xiaona Chen, Yuyan Jiang, Chi Zhang, Shasha He, Hangxiang Wang, Kanyi Pu. Renal clearable polyfluorophore nanosensors for early diagnosis of cancer and allograft rejection. Nature Materials. 2022, 21, 598-607. (IF= 47.56)
  8. Jiaguo Huang, Jingchao Li, Yan Lyu, Qingqing Miao, and Kanyi Pu. Molecular optical imaging probes for early diagnosis of drug-induced acute kidney injury. Nature Materials. 2019, 18, 1133-1143. (IF= 47.56)
  9. Luling Wu#, Jiaguo Huang#, Kanyi Pu, Tony D. James. Dual-locked spectroscopic probes for sensing and therapy. Nature Reviews Chemistry, 2021, 5, 406-421. (IF= 34.57，共同一作)
  10. Jiaguo Huang, Shiyun Xian, Yi Liu, Xiaona Chen, Kanyi Pu, Hangxiang Wang. A Renal clearable activatable polymeric nanoprobe for early detection of hepatic ischemia-reperfusion injury. Advanced Materials. 2022, 2201357. (IF= 32.08)
  11. Jiaguo Huang, Yuyan Jiang, Jingchao Li, Shasha He, Jingsheng Huang, Kanyi Pu. A renal-clearable macromolecular reporter for near-infrared fluorescence imaging of bladder cancer. Angew Chem Int Ed. 2020, 59, 4415-4420. (IF=16.82)
  12. Jiaguo Huang, Chen Xie, Xiaodong Zhang, Yuyan Jiang, Jingchao Li, Quli Fan, Kanyi Pu. Renal-clearable molecular semiconductor for second near-infrared fluorescence imaging of kidney dysfunction. Angew Chem Int Ed. 2019, 58, 15120-15127. (IF=16.82)
  13. Jiaguo Huang, Yan Lyu, Jingchao Li, Penghui Cheng, Yuyan Jiang, Kanyi Pu. A renal-clearable duplex optical reporter for real-time imaging of contrast-induced acute kidney injury. Angew Chem Int Ed. 2019, 58, 17796-17804. (IF=16.82)
  14. Jiaguo Huang, Kanyi Pu. Activatable molecular probes for second near-infrared fluorescence, chemiluminescence, and photoacoustic Imaging. Angew Chem Int Ed. 2020, 59, 11717-11731. (IF=16.82)
  15. Jingsheng Huang#, Jiaguo Huang#, Penghui Cheng, Yuyan Jiang, Kanyi Pu. Near-infrared chemiluminescent reporters for in vivo imaging of reactive oxygen and nitrogen species in kidneys. Advanced Functional Materials, 2020, 30, 2003628. (IF=18.80，共同一作)
  16. Jiaguo Huang, Kanyi Pu. Near-infrared fluorescent molecular probes for imaging and diagnosis of nephro-urological diseases. Chemical Science, 2021, 12, 3379-3392. (IF= 9.83)
  17. Jiaguo Huang, Stefanie Weinfurter, Cristina Daniele, Rossana Perciaccante, Rodeghiero Federica, Leopoldo Della Ciana, Johannes Pilla and Norbert Gretz. Zwitterionic near infrared fluorescent agents for noninvasive real-time transcutaneous assessment of kidney function. Chemical Science, 2017, 8, 2652-2660. (IF= 9.83)

部分發明專利  

  1. 黃佳國，劉彪翔，柳乂。一種生物标志物響應型熒光示蹤劑及其制備方法和應用 (202111482551.2)
  2. 黃佳國、柳乂、阮班康、周娅。一種近紅外二區熒光化合物及其制備方法與應用 （202211727312.3）
  3. Kanyi Pu, Jiaguo Huang. Molecular renal reporters for real-time optical imaging of drug-induced acute kidney injury. Application number: 10201900965U.
  4. Della Ciana Leopoldo, Gretz Norbert, Perciaccante Rossana, Rodeghiero Federica, Geraci Stefania, Huang Jiaguo, Herrera Pérez Zeneida, Pill Johannes, Weinfurter Stefanie. Novel tricarbocyanine-cyclodextrin(s) conjugates and uses thereof. Application number: US20150328342A1.
  5. Gretz Norbert, Rudolf Rüdiger, Weinfurter Stefanie, Brenna Cinzia, Huang Jiaguo, Khan Arif ul Maula. Means and Methods for Visualization of Tissue Structures. Application number: PCT/EP2017/081034.
  6. Wenbin Zeng, Zhiguo Liu, Jiaguo Huang. Dansyl molecular probe and synthetic method and application thereof. Application number: CN201010183549