教育經曆
2009-09 -2013-06 沈陽藥科大學 太阳集团1088vip 藥學學士
2013-09 -2018.06 沈陽藥科大學 太阳集团1088vip 藥劑學博士
2017.09 -2018.06 Purdue University 太阳集团1088vip 博士聯合培養
2018.07-2020.10 Purdue University 太阳集团1088vip 藥劑學 博士後
科研項目及成果
1.基于後發性白内障防治的金雀異黃素陽離子納米緩釋-人工晶體載藥系統的構建與評價
(國家自然基金,項目編号:81100654, 2012.09-2014.12)
2.基于提高藥物角膜透過性的奈帕芬胺眼部傳遞系統的設計與評價(2015.05-2017.07)
3.Advancing innovative therapies against pandrug-resistant Gram-negative superbugs(美國NIH 基金,項目編号:R01 AI146160, $3,247,904)
發表論文情況
1.Yu Shihui, Zhang, X., Tan, G., Tian, L., Liu, D., Liu, Y., ... & Pan, Weisan*. A novel pH-induced thermosensitive hydrogel composed of carboxymethyl chitosan and poloxamer cross-linked by glutaraldehyde for ophthalmic drug delivery. Carbohydrate Polymers, 2017, 155:208-217. (IF=7.182, JCR:1)
2.Yu Shihui, Tan G, Liu D, et al. Nanostructured lipid carrier (NLC)-based novel hydrogels as potential carriers for nepafenac applied after cataract surgery for the treatment of inflammation: design, characterization and in vitro cellular inhibition and uptake studies[J]. RSC advances, 2017, 7(27): 16668-16677. (IF=3.119, JCR:3)
3.Yu Shihui, Li Q, Li Y, et al. A novel hydrogel with dual temperature and pH responsiveness based on a nanostructured lipid carrier as an ophthalmic delivery system: enhanced trans-corneal permeability and bioavailability of nepafenac[J]. New Journal of Chemistry, 2017, 41(10): 3920-3929. (IF=3.288, JCR:3)
4.Yu Shihui, Wang, Q. M., Wang, X., Liu, D., Zhang, W., Ye, T., ... & Pan, Weisan*. Liposome incorporated Ion sensitive in situ gels for opthalmic delivery of Timolol Maleate. International Journal of Pharmaceutics, 2015, 480(1–2):128-136. (IF=4.845, JCR:2).
5.Yu Shihui, Wang S, Zou P, et al. Inhalable liposomal powder formulations for co-delivery of synergistic ciprofloxacin and colistin against multi-drug resistant gram-negative lung infections[J]. International Journal of Pharmaceutics, 2020, 575: 118915. (IF=4.845,JCR:2, 共第一)
6. Yu Shihui, Yuan H, Chai G, et al. Optimization of inhalable liposomal powder formulations and evaluation of their in vitro drug delivery behavior in Calu-3 human lung epithelial cells[J]. International Journal of Pharmaceutics, 2020: 119570. (IF=4.845, JCR:2)
7. Wang Shaoning, Yu Shihui, Lin, Y., Zou, P., Chai, G., Heidi, H. Y., ... & Zhou, Qi*. Co-Delivery of Ciprofloxacin and Colistin in Liposomal Formulations with Enhanced In Vitro Antimicrobial Activities against Multidrug Resistant Pseudomonas aeruginosa. Pharmaceutical research, 2018, 35(10): 187. (IF=3.896, JCR:3, 共第一)
8. Dandan Liu, Shihui Yu, Z Zhu, et al. Controlled delivery of carvedilol nanosuspension from osmotic pump capsule: in vitro and in vivo evaluation. International Journal of Pharmaceutics, 2014, 475(1–2):496-503. (IF=4.845)
9. Yingna Xue, Shihui Yu, H Wang, et al. Design of a timed and controlled release osmotic pump system of atenolol. Drug Development and Industrial Pharmacy, 2015, 41(6):2877 - 2884. (IF=2.429)
10. Guoxin Tan, Shihui Yu, H Pan, et al. Bioadhesive chitosan-loaded liposomes: a more efficient and higher permeable ocular delivery platform for timolol maleate. International Journal of Biological Macromolecules, 2017, 94, 355-363. (IF=5.162)
11. Guoxin Tan, Shihui Yu, Jinyu Li, Weisan Pan*. Development and characterization of nanostructured lipid carriers based chitosan thermosensitive hydrogel for delivery of dexamethasone. International Journal of Biological Macromolecules, 2017, 103, 941-947. (IF=5.162)
申請專利2項
1.朱志紅,潘衛三,曲緒楷,楊星鋼,梁靜閣,李淑娟,于世慧
鹽酸曲美他嗪雙層滲透泵控釋片及制備方法。中國發明專利:201410013277.8;103735528B.
2.潘衛三,張文骥,孔郡,李雪東,陳奮,于世慧,李靜,李三鳴
一種金雀異黃素陽離子納米脂質載體及其制備方法. 中國發明專利:CN 103271892.
會議論文1篇
1.首屆全國藥學類研究生學術論壇,Shihui Yu, Guoxin Tan, Dandan Liu, Xinggang Yang*, Weisan Pan*. Nanostructured lipid carrier (NLC)-based novel hydrogels as potential carriers for nepafenac applied after cataract surgery for the treatment of inflammation: design, characterization and in vitro cellular inhibition and uptake studies. (南京,中國,2017年5月)
獲獎情況
1.2016-2017學年榮獲國家獎學金,一等學業獎學金;
2.2015-2016學年榮獲博愛新開源研究生企業獎學金,一等學業獎學金;
3.2014-2015學年榮獲卡樂康研究生企業獎學金,一等學業獎學金;
4.2017.02榮獲教育部科學技術進步二等獎(第8完成人)