藥學前沿大講堂第257講

題目: Delivering HIV Prevention through Polymeric Thin Films

報告人: Lisa Cencia Rohan 教授，美國匹茲堡大學

主持人: 徐峻教授，太阳集团1088vip

時間: 2016年9月3日（周六）14:00-15:00

地點: 中山大學東校區行政樓B101

報告人簡介:

Lisa Cencia Rohan, Ph.D holds appointments as Professor in the Department of Pharmaceutical Sciences in the School of Pharmacy and the Department of Obstetrics, Gynecology & Reproductive Sciences and the Clinical & Translational Science Institute in the School of Medicine at the University of Pittsburgh. She also is an Investigator at the Magee-Womens Research Institute. Dr. Rohan additionally serves as the Co-Director for the Comparative Assessment Core of the Central Laboratory for the Microbicide Trials Network (MTN). The MTN is a U.S. National Institutes of Health-funded worldwide collaborative clinical trials network focused on preventing the sexual transmission of  HIV spanning 9 countries and 32 sites.  

Dr. Rohan obtained a B.S. in chemical engineering from West Virginia University and a Ph.D. in Pharmaceutics from the University of Pittsburgh. She completed her Postdoctoral Fellowship in the area of Mucosal Immunology. Prior to joining academics, Dr. Rohan spent several years in industry within the Drug Development groups of Sterling Winthrop Pharmaceuticals and Kodak Pharmaceuticals, and was formerly the Director of Clinical Studies at Biodecision Laboratories.  The focus of her research program is in the development of mucosal drug delivery systems.  Specific therapeutic areas of interest are women’s health, gynecologic oncology, irritable bowel disease, vaccines, contraception and HIV prevention. The Rohan lab was the first to develop and clinically test vaginal films intended to protect women from acquisition of HIV.  The lab is further developing this technology to co-deliver anti-HIV drugs with contraceptives in the hopes of enhancing reproductive aged women’s willingness to use such products.  Research efforts are also ongoing toward the development of oral vaccine film dosage forms which do not require cold chain storage to overcome this significant problem with respect to global distribution of vaccines especially in the developing world.  Product development efforts ongoing in the laboratory are complemented by projects focused on the development of biologically relevant in vitro models and efforts to define the role of chemical, physical, and biological aspects of vaginal and cervical tissues and fluids in the development of vaginal and cervical products.

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