學術講座080923（地點已更改）
學 術 講 座
1. General talk Title: "Neurobiology of Schizophrenia"
主講人：Lalit Srivastava Associate Professor
Department of Psychiatry
主持人： 鄭文華 教 授 太阳集团1088vip
講座内容：An overview of the behavioral and neurobiological abnormalities in schizophrenia will be presented. Recent studies on the role of dopamine, glutamate and GABA as well as genes implicated in schizophrenia will also be reviewed.
時間：2008年9月23日星期二下午3:00-4:30
地點：東校區教學樓C401
2. Research talk Title: "Brain Development and Schizophrenia: Studies in Neonatal Hippocampus-Lesioned Animals"
主講人：Lalit Srivastava Associate Professor
Department of Psychiatry
主持人：鄭文華 教 授 太阳集团1088vip
講座内容：It is believed that genetic and environmental risk factors cause schizophrenia by changing normal developmental pattern of the brain. The exact nature of neurodevelopmental abnormalities remains unknown; however, they are presumed to lay down faulty neural circuits impacting brain chemistry and functions in adulthood. Anatomical abnormalities in the temporal lobe including the hippocampal formation are widely reported in persons affected with schizophrenia. To understand the importance of normal development of hippocampus in adult behaviors, we introduce defined hippocampus lesions in rats at neonatal ages. The neonatal ventral hippocampus lesioned (NVHL) rats show a variety of schizophrenia related behaviors when they reach post-pubertal age. Our work as well as studies by other investigators has shown a fundamental abnormality in the structure and function of the prefrontal cortex in NVHL rats. In this seminar, I will discuss our results showing possible neurochemical and molecular mechanisms that may be responsible for delayed behavioral changes after NVH lesions. It is hoped that these investigations will help us better understand the neurobiological mechanisms underlying schizophrenia.
時間：2008年9月25日星期四下午3:00-4:30
地點：東校區教學樓C401
Lalit Srivastava副教授簡介：Lalit Srivastava現任加拿大McGill大學道格拉斯精神衛生中心副教授。1983年獲Jawaharlal Nehru大學生命科學博士學位。1985-1992在加拿大McMaster大學從事博士後研究工作。自1992年起，在McGill大學從事神經精神藥理學研究，主要研究領域涉及動物模型在精神病研究中的應用、精神病發病過程中的生化改變、神經系統發育與精神病之間的關系以及神經退行性疾病發生的生化基礎，是國際著名的精神病學科專家，在精神病動物模型的制備和海馬損傷模型等領域有獨特的造詣。
歡迎各位師生踴躍參加！