澳大利亞Hak-Kim?Chan教授學術講座081127
講座題目:Dry Powder Inhalation Aerosol Delivery–from Particle
Production to Lung Deposition
主 講 人:Dr Hak-Kim Chan Professor in Pharmaceutics (Advanced
Drug Delivery),
主 持 人:吳傳斌 教授 太阳集团1088vip副院長
講座時間:2008年11月27日下午三點
講座地點:太阳集团1088vip講學廳(125室)
講座摘要:Driven by the pharmaceutical industry to realise the full potential of the lungs for local and systemic treatment of diseases, pulmonary drug delivery by inhalation aerosols has been undergoing rapid development in the past decade. This has led to novel research of aerosol delivery devices coupled to the formulations and new technologies that are required to produce particles of defined characteristics for improved delivery. This lecture highlights some of the recent advances in this expanding field.
主講人簡介:
* Employments and education: Professor (University of Sydney) 2007-present; Associate Professor 2002-2006; Senior Lecturer 1999-2001; Lecturer 1995-1998; Scientist (Genentech Inc.,
* Over 200 scientific publications on pharmaceutical formulation and drug delivery (with a strong focus on inhalation aerosols), including 140 original research papers, 32 book chapters and reviews and over 100 conference articles, with over 1200 non-self citations.
* Fellow of the American Association of Pharmaceutical Scientists 2006.
* John A Brodie Medal in 1999 by the Australian Institute of Engineers for achievement on processing of pharmaceutical powders for inhalation.
* Awarded the Sigma Drug Delivery Prize in 1989 for research on inhalation aerosols.
*Conference and symposium chairs: Australian Aerosol Symposium (an international aerosol symposium jointly sponsored by the International Society for Aerosols in Medicine, ANZSRS, and TSANZ), 2001; Symposium on Nanoparticles for Therapeutic Applications, 7th World Biomaterials Congress 2004; RACI Pharmaceutical Science Group Inaugural Research Student Symposium 2005; Fluid/particle systems in Pharmaceutical Industry (Session Co-Chair), 5th World Congress on Particle Technology 2006. Conference organising committees: ETOPIM7, Sydney 2006 (responsible for the bio-composite session); The 15th International Congress of ISAM, Perth 2005 (responsible for the entire pharmaceutical industry program); International Workshop on High Gravity Technology, Beijing 2005 (the pharmaceutical session).
* Invited major conference speakers: AAPS (San Antonio 92); AIChE (Denver 94); APSA (Melbourne 95&96); ANZSRS (Perth 95); ISAM (Vienna 99); TSANZ (Brisbane 01); ISNMT (Beijing 01); WCPT4 (Sydney 02); WBC7 (Sydney 04); ISAM (Perth 05); LB 11 (Hokkaido 05); IWHGT (05 Beijing); NEPTIS-15 (Awajishima 06); Bioaerosol Workshop (Sydney 06); RDD- Europe (Paris 07);AASP (Philippines 07); PPIPC (Nagoya 08); RGJ Congress IX (Pattaya 08).
* Six patents and pending patents on powder and aerosol formulations. (i) WO 9523613 Pharmaceutical Acceptable DNase Inhalant, 1995; (ii) WO 9523854 Improved DNase Liquid Solutions Using Calcium and Sugars to Enhance Storage, 1995; (iii) WO 0245690 Synthesis of Small Particles of Biologically Active Agents, such as pH-sensitive Proteins; (iv) WO 0294342 European Patent EP 1 389 137 B Compositions for Protein Delivery via the Pulmonary Route; (v) WO 0696906 Inhalable drug; (vi) Australian provisional patent ‘Composite carriers for dry powder inhalation therapy’ June 2007.